Garbutt on ABC: baclofen not a silver bullet for alcoholism

Clinton wrote this …

James Garbutt was on ABC’s Good Morning America today responding to a story about a French cardiologist who claims a single medication, baclofen, helped him control his addiction to alcohol. (The BBC also ran the story.)

The book may be new; the discussion isn’t. See this JAMA letter.

Garbutt is a professor of Psychiatry and medical director of the Alcohol and Substance Abuse Program and an investigator in UNC’s Bowles Center for Alcohol Studies.

Baclofen is not a cure, Garbutt says, but he and others have found that it does a good job of controlling the negative side effects people with alcoholism experience as they begin to abstain.

Garbutt was lead author of one of the first published trials of long-acting Naltrexone, and, with Dr. Alexie Kampov of UNC, has investigated the role of “sweet-liking” as a risk factor for alcoholism and as a predictor of response to Naltrexone. He has conducted the only double-blind trial of baclofen in the US and is currently leading a placebo-controlled trial of the drug combine with Naltrexone.

He told ABC, “If you put baclofen and Naltrexone together, you get a bigger  bang for your buck.”

3 Comments

Filed under From the lab, From the media

3 Responses to Garbutt on ABC: baclofen not a silver bullet for alcoholism

  1. i drank gin on bacolfen. i have also quit drinking on bacolfen. i have been on bacolfen 26+years since my accident. i think i used willpower to stop imbibing, but who knows. i hope bacolfen does indeed work for alcoholics and their loved ones, because alcohol ruins ppl’s lives.

  2. I agree that baclofen is very effective in taking the edge off, especially in the early weeks and months of sobriety. I applaud people like Dr. Ameisen for being brave enough to step outside the box.

    I am fortunate to have a doctor who is very open-minded. I explained my situation and then showed him the book. I also printed out several web articles for him to see the proof. Thankfully, he started me on a fairly high dose and then raised it again after a month when he realized I was OK with it.

    Thanks for the post!

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